Introduction to Toxicology, 3rd Edition by Timbrell, John A

Bibliographic Information:
Title: Introduction to Toxicology
Editor: Timbrell, John A
Edition: 3rd
Publisher: Taylor & Francis
Length: 228 pages
Size: 2.79 MB
Language: English

As with many areas of biomedical science, the study of toxicology has been influenced by fundamental changes in biochemistry and molecular biology and now by the newly emerging sciences of genomics, proteomics and metabonomics. These are having a major impact on the study and potentially an understanding of the interactions of chemicals with living sytems. Also new areas and types of interaction have emerged since the second edition of this book. Some of these, such as interactions with the peroxisome proliferator activated receptor, are now mentioned in this new edition.

However, this book is primarily concerned with the basic underlying principles of toxicology at the introductory level and these remain largely unchanged. Therefore the format of the previous editions has been retained with specific examples used to illustrate these basic principles. The major changes have been updating the existing text in relation to new knowledge or nomenclature and the inclusions of new examples.

Thus there is now a much enlarged section on risk assessment and new sections on in vitro toxicology, on endocrine disrupters and on the treatment of posioning, for example. A number of specific case studies for particular chemicals or toxins have also been included. This third edition now has chapter outlines and summaries and questions with answers, as teaching aids. For those requiring more extensive and detailed information there are a number of excellent reference texts which are listed in the bibliography at the end of each chapter.

The number of chemicals used in society will inevitably increase and consequently so will the risk of chemical exposure, even though the use and manufacture of chemicals may now be better regulated. Thus despite the recent regrettable closure, contraction or realignment of research institutions and courses specifically orientated towards toxicology in the UK, the subject of toxicology is no less important to our society. Therefore, scientists with a broad overview of toxicology will always be required as well as more specialized scientists such as molecular biologists. I hope that this book will helpin that endeavour by stimulating an interest in toxicology.

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